Large-scale epidemiology of opisthorchiasis in 21 provinces in Thailand based on diagnosis by fecal egg examination and urine antigen assay and analysis of risk factors for infection
Application of the antigen assay to diagnose O. viverrini infection yielded a four-fold higher prevalence than the fecal egg examination, with the highest difference in low endemicity regions, which suggests that previous surveys may have underestimated the extent of opisthorchiasis in Thailand. Given the ease of urine sample collection, our study highlights the potential for application of the antigen assay as a new tool in the control of opisthorchiasis.
Authors
- Anchalee Techasen (ORCID: https://orcid.org/0000-0002-4230-5641)
- Phattharaphon Wongphutorn
- Paiboon Sithithaworn (ORCID: https://orcid.org/0000-0002-9480-1778)
- Melissa Haswell (ORCID: https://orcid.org/0000-0002-4067-7951)
- Chanika Worasith
- Narong Khuntikeo (ORCID: https://orcid.org/0000-0001-9305-0688)
- Watcharin Loilome (ORCID: https://orcid.org/0000-0001-8572-5577)
- Attapol Titapun (ORCID: https://orcid.org/0000-0001-7492-321X)
- Simon D. Taylor‐Robinson (ORCID: https://orcid.org/0000-0002-8811-1834)
- Nisana Namwat (ORCID: https://orcid.org/0000-0002-6743-5047)
- Thomas Crellen (ORCID: https://orcid.org/0000-0003-2934-1063)
- Bandit Thinkhamrop (ORCID: https://orcid.org/0000-0002-6486-1948)
- Kulthida Y. Kopolrat (ORCID: https://orcid.org/0000-0001-6114-6554)
- Chaiwat Tawarungruang
- Chatanun Eamudomkarn (ORCID: https://orcid.org/0000-0002-6193-9842)
- Samarn Futrakul
Institutions
- The University of Sydney (AU)
- Queensland University of Technology (AU)
- National University of Singapore (SG)
- Khon Kaen University (TH)
- Kasetsart University (TH)
- University of Oxford (GB)
- Office of Disease Prevention (US)
- National University Health System (SG)
- Sakon Nakhon Rajabhat University (TH)
- Imperial College London (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1371/journal.pntd.0013095
- Citations
- 1
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Wellcome Trust
- National Research Council of Thailand
- Kadoorie Charitable Foundation
- NIHR Imperial Biomedical Research Centre