[<i>Qianggu Kangshu</i> Formula attenuates osteoclast differentiation in rheumatoid arthritis by inhibiting the HIF-1α/BNIP3 autophagy signaling pathway].
QGKSF attenuates RANKL-induced osteoclast differentiation in hypoxic RAW264.7 cells by inhibiting the HIF-1α/BNIP3 autophagy signaling pathway, suggesting its potential for treatment of bone destruction in rheumatoid arthritis.
Authors
- Li‐Min Huang (ORCID: https://orcid.org/0000-0002-9291-260X)
- Zongxing Zhang (ORCID: https://orcid.org/0000-0003-2967-3367)
- Bao Zhang (ORCID: https://orcid.org/0000-0003-0320-2305)
- Yuan Lin (ORCID: https://orcid.org/0000-0001-5449-3435)
- Lu Jiang (ORCID: https://orcid.org/0000-0003-2885-0333)
- Dan Chen (ORCID: https://orcid.org/0000-0001-7665-7787)
- Weiyi Li (ORCID: https://orcid.org/0000-0002-0162-6107)
Institutions
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Institute for Rheumatic Diseases (Japan) (JP)
- Minda Hospital (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-07-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.07.05
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article