Artificial intelligence-enhanced electrocardiography to predict regurgitant valvular heart diseases: an international study
This study developed AI-ECG models to diagnose and predict rVHDs and validated the models in a transnational and ethnically distinct cohort. The AI-ECG models could be utilized to guide surveillance echocardiography in patients at risk of future rVHDs, to facilitate early detection and intervention.
Authors
- Yixiu Liang (ORCID: https://orcid.org/0000-0001-5467-8958)
- Joseph Barker (ORCID: https://orcid.org/0000-0002-5483-9608)
- Konstantinos Patlatzoglou (ORCID: https://orcid.org/0000-0002-5888-8490)
- Libor Pastika (ORCID: https://orcid.org/0000-0001-6892-6553)
- Hongyang Lu (ORCID: https://orcid.org/0000-0002-4077-6802)
- Ewa Sieliwończyk (ORCID: https://orcid.org/0000-0002-8603-7044)
- Daniel B. Kramer (ORCID: https://orcid.org/0000-0003-4241-3586)
- Nicholas S. Peters (ORCID: https://orcid.org/0000-0002-1014-7052)
- Arunashis Sau (ORCID: https://orcid.org/0000-0002-0204-7078)
- Junbo Ge (ORCID: https://orcid.org/0000-0002-8765-4941)
- Zachary I. Whinnett (ORCID: https://orcid.org/0000-0002-2775-5126)
- Fu Siong Ng (ORCID: https://orcid.org/0000-0002-8681-4368)
- Jonathan W. Waks (ORCID: https://orcid.org/0000-0001-5560-5638)
- Boroumand Zeidaabadi (ORCID: https://orcid.org/0009-0004-0025-9896)
- Xi Liu (ORCID: https://orcid.org/0000-0001-6924-5119)
- Shuo Wang (ORCID: https://orcid.org/0000-0002-2947-8783)
- Yangang Su (ORCID: https://orcid.org/0000-0003-4801-8595)
- Ziqing Yu (ORCID: https://orcid.org/0009-0006-2743-445X)
Institutions
- Beth Israel Deaconess Medical Center (US)
- Shanghai Medical College of Fudan University (CN)
- Harvard University (US)
- University of Antwerp (BE)
- Imperial College Healthcare NHS Trust (GB)
- Fudan University (CN)
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- Hammersmith Hospital (GB)
- Antwerp University Hospital (BE)
- NIHR Imperial Biomedical Research Centre (GB)
- Medtronic (China) (CN)
- MRC London Institute of Medical Sciences (GB)
- Deaconess Hospital (US)
- Imperial College London (GB)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1093/eurheartj/ehaf448
- Citations
- 10
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 13.88
Funders
- National Institute for Health and Care Research
- British Heart Foundation
- Fudan University
- Medical Research Council Canada
- Barwon Health Foundation
- Medical Research Council
- NIHR Imperial Biomedical Research Centre