Leptin receptor polymorphism increases the risk of painful symptoms in Brazilian women with endometriosis.
Our findings suggest that the <i>LEPR</i> rs1137100 polymorphism is associated with increased endometriosis-related gynecological pain and may be a potential target for molecular diagnosis of the disease and development of individualized treatment strategies.
Authors
- Plínio Tostes Berardo (ORCID: https://orcid.org/0000-0002-4426-699X)
- Rui Medeiros (ORCID: https://orcid.org/0000-0003-3010-8373)
- Daniel Escorsim Machado (ORCID: https://orcid.org/0000-0002-2640-8579)
- Jéssica Vilarinho Cardoso (ORCID: https://orcid.org/0000-0002-6758-3664)
- Jamila Alessandra Perini (ORCID: https://orcid.org/0000-0002-7683-0698)
- Fernanda Almeida
Institutions
- Universidade do Estado do Rio de Janeiro (BR)
- Hospital Federal dos Servidores do Estado (BR)
- IPO Porto (PT)
- Escola Nacional de Saúde Pública (BR)
- Instituto Superior de Educação do Rio de Janeiro (BR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.61622/rbgo/2025rbgo43
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00