Cutaneous Mucormycosis in a Patient With Cirrhosis: A Case Report

The global incidence of invasive mucormycosis (mucor) infection is on the rise due in part to an increased utilization of immunosuppressive therapies to treat malignancies and autoimmune diseases. While cirrhosis has previously been considered a risk factor for fungal infections, very little is known about the inciting factors precipitating development of isolated cutaneous mucormycosis infection. This form of mucor poses a significant mortality risk despite antifungal and surgical treatments and has been documented in only 5 patients with cirrhosis prior to our case report. This case report presents the sixth documented case of cutaneous mucormycosis in a patient with cirrhosis and explore nosocomial etiologies for its progression to clinically significant infection.

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Journal
Journal of Investigative Medicine High Impact Case Reports
Published
2025-05-01
DOI
https://doi.org/10.1177/23247096251356334
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Cutaneous Mucormycosis in a Patient With Cirrhosis: A Case Report

Lu An, Roma Mehta, Margaret Kypreos, Haley Belt et al.
Journal of Investigative Medicine High Impact Case Reports
Antifungal resistance and susceptibility
article

Cutaneous Mucormycosis in a Patient With Cirrhosis: A Case Report

Lu An, Roma Mehta, Margaret Kypreos, Haley Belt, Ginna Hernandez-Velasquez
article en

Abstract

The global incidence of invasive mucormycosis (mucor) infection is on the rise due in part to an increased utilization of immunosuppressive therapies to treat malignancies and autoimmune diseases. While cirrhosis has previously been considered a risk factor for fungal infections, very little is known about the inciting factors precipitating development of isolated cutaneous mucormycosis infection. This form of mucor poses a significant mortality risk despite antifungal and surgical treatments and has been documented in only 5 patients with cirrhosis prior to our case report. This case report presents the sixth documented case of cutaneous mucormycosis in a patient with cirrhosis and explore nosocomial etiologies for its progression to clinically significant infection.

Journal of Investigative Medicine High Impact Case ReportsVol. 13
The University of Texas Southwestern Medical Center (US)
Good health and well-being
Openalex Percentile: Top 78%
Antifungal resistance and susceptibility
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Cutaneous Mucormycosis in a Patient With Cirrhosis: A Case Report — Lu An, Roma Mehta, et al. · Journal of Investigative Medicine High Impact Case Reports (2025) | TGRS Research Map | TGRS