[A stable mouse model of chronic liver fibrosis induced by vitamin A deficiency and intraperitoneal CCl<sub>4</sub> injection].

Feeding with diet containing 500 IU/kg VA for 4 weeks and 10 mL/kg CCl<sub>4</sub> injections for 8 weeks can result in stable moderate to severe liver fibrosis in mice without spontaneous reversal at 8 weeks of drug withdrawal.

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Publication Details

Journal
PubMed
Published
2025-07-20
DOI
https://doi.org/10.12122/j.issn.1673-4254.2025.07.20
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

[A stable mouse model of chronic liver fibrosis induced by vitamin A deficiency and intraperitoneal CCl4 injection].

Tingting Yang, Li Zhao
PubMed
Liver Disease Diagnosis and Treatment
article

[A stable mouse model of chronic liver fibrosis induced by vitamin A deficiency and intraperitoneal CCl4 injection].

Tingting Yang, Li Zhao
article en

Abstract

Feeding with diet containing 500 IU/kg VA for 4 weeks and 10 mL/kg CCl<sub>4</sub> injections for 8 weeks can result in stable moderate to severe liver fibrosis in mice without spontaneous reversal at 8 weeks of drug withdrawal.

PubMedVol. 45(7)
Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Good health and well-being
Liver Disease Diagnosis and Treatment
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[A stable mouse model of chronic liver fibrosis induced by vitamin A deficiency and intraperitoneal CCl<sub>4</sub> injection]. — Tingting Yang, Li Zhao · PubMed (2025) | TGRS Research Map | TGRS