Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer
KRT6A promotes EMT and metastasis in TNBC via Wnt/β-catenin signaling, contributing to LVI and chemoresistance. It may serve as a prognostic biomarker and therapeutic target in TNBC.
Authors
- Linyue Hai (ORCID: https://orcid.org/0000-0002-3082-7741)
- Yiping Zou (ORCID: https://orcid.org/0000-0003-2880-2147)
- Ran Meng (ORCID: https://orcid.org/0000-0002-5267-5662)
- Xianhui Ruan (ORCID: https://orcid.org/0000-0003-3049-7532)
- Yantao Jiang
- Wei Luo (ORCID: https://orcid.org/0000-0002-8845-903X)
- Yao Wang (ORCID: https://orcid.org/0000-0002-9352-422X)
- Wenbo Liu (ORCID: https://orcid.org/0000-0002-2270-9606)
- Yue Yu (ORCID: https://orcid.org/0000-0001-8266-641X)
- Xi Ma
- Yuxiao Liu (ORCID: https://orcid.org/0000-0002-4147-9797)
- Wenbin Jia
- Shuyue Guo (ORCID: https://orcid.org/0000-0002-4780-2794)
- X B Cao
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-07-14
- DOI
- https://doi.org/10.4143/crt.2025.423
- Primary Topic
- Skin and Cellular Biology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China