Evaluation of Diagnostic Parameters of Cytodiagnostics as a screening tool conducted in 2005–2020 as part of the National Population-Based Cervical Cancer Screening Program in Poland

The prevention program significantly improved the detection parameters of the in-program as compared to out-program cytodiagnostics. The goal of the screening programs should be to identify lesions consistent with ≥ CIN2. Molecular testing, which can identify at least 14 HPV HR genotypes, should be the first-line screening tool. A positive molecular test result should not be an indication for advanced diagnostics. Other than conventional or liquid-based cytology, an ultimate detection test is necessary.