Safety of topical tobramycin powder during operative treatment of fractures
A single dose of 1200 mg tobramycin powder administered locally during fracture fixation of the tibia does not lead to nephrotoxic serum levels or long-term changes to renal function.
Authors
- Sara Lee
- R. Castillo (ORCID: https://orcid.org/0000-0003-0473-5891)
- Nathan N. O’Hara (ORCID: https://orcid.org/0000-0003-0537-3474)
- Gregory M. Schrank (ORCID: https://orcid.org/0000-0001-9030-4224)
- Yasmin Degani (ORCID: https://orcid.org/0000-0001-6485-9285)
- Anthony R. Carlini (ORCID: https://orcid.org/0000-0003-1419-4515)
- Robert V. O’Toole (ORCID: https://orcid.org/0000-0002-5628-6584)
- Suna Chung
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland Medical Center (US)
- Johns Hopkins University (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1093/jac/dkaf230
- Citations
- 1
- Primary Topic
- Surgical site infection prevention
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- U.S. Department of Defense