Inhibitory Effects of 3′,4′‐Dihydroxyflavonol in a Rabbit Model of Minimally Invasive Bleb Surgery With <scp>PreserFlo MicroShunt</scp>
DiOHF inhibited scarring following implantation of PFMS in rabbit eyes by reducing local oxidative stress, inflammation and fibroblastic activity. DiOHF may be a safer and more effective wound modulating agent than the conventional use of MMC.
Authors
- Roy C. K. Kong (ORCID: https://orcid.org/0000-0002-7881-9847)
- Elsa C. Chan (ORCID: https://orcid.org/0000-0002-6604-5426)
- Jennifer C. Fan Gaskin (ORCID: https://orcid.org/0000-0003-2782-9700)
- Zoe Pasvanis (ORCID: https://orcid.org/0000-0002-1162-5378)
Institutions
- The University of Melbourne (AU)
- St Vincent's Hospital Melbourne (AU)
- The Royal Victorian Eye & Ear Hospital (AU)
- Centre for Eye Research Australia (AU)
Publication Details
- Journal
- Clinical and Experimental Ophthalmology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1111/ceo.14578
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- BrightFocus Foundation
- Australian Government
- University of Melbourne