Association between the triglyceride-glucose-waist-to-height ratio and early arterial stiffness in cardiovascular-kidney-metabolic syndrome

The TyG-WHtR index is significantly associated with arterial stiffness and may offer potential value in vascular risk evaluation in patients with CKM syndrome, demonstrating a particularly strong correlation with baPWV during early disease stages (0-1), independent of conventional cardiovascular risk factors. Notably, this index exhibits superior predictive performance compared to existing TyG variants, with enhanced clinical utility for risk stratification, especially in male populations.

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Publication Details

Journal
European journal of medical research
Published
2025-07-16
DOI
https://doi.org/10.1186/s40001-025-02881-0
Citations
3
Primary Topic
Cardiovascular Health and Disease Prevention
Type
article
Field-Weighted Citation Impact
4.16

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article

Association between the triglyceride-glucose-waist-to-height ratio and early arterial stiffness in cardiovascular-kidney-metabolic syndrome

Zekai Chen, Yuexiang Qin, Yejun He, Yu Cao et al.
3 citations
European journal of medical research
Cardiovascular Health and Disease Prevention
4.16
article

Association between the triglyceride-glucose-waist-to-height ratio and early arterial stiffness in cardiovascular-kidney-metabolic syndrome

Zekai Chen, Yuexiang Qin, Yejun He, Yu Cao, Fang Wang
article en
3 citations

Abstract

The TyG-WHtR index is significantly associated with arterial stiffness and may offer potential value in vascular risk evaluation in patients with CKM syndrome, demonstrating a particularly strong correlation with baPWV during early disease stages (0-1), independent of conventional cardiovascular risk factors. Notably, this index exhibits superior predictive performance compared to existing TyG variants, with enhanced clinical utility for risk stratification, especially in male populations.

European journal of medical researchVol. 30(1)
Central South University (CN), Third Xiangya Hospital (CN)
National Natural Science Foundation of China, Central South University, China Postdoctoral Science Foundation, Natural Science Foundation of Hunan Province, Xiangya Hospital, Central South University
Good health and well-being
Openalex Percentile: Top 5%
Cardiovascular Health and Disease Prevention
4.16
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