Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats.
Shilajit exhibited significant protective effects against 5-FU-induced nephrotoxicity, improving oxidative parameters, protein expression, and kidney histopathology. Further studies are needed to elucidate its molecular mechanism and therapeutic potential.
Authors
- Emine Atakişi (ORCID: https://orcid.org/0000-0002-5685-1870)
- Melek Öztürkler (ORCID: https://orcid.org/0000-0002-2917-6371)
- Mehmet Ezer (ORCID: https://orcid.org/0000-0003-4422-6768)
- Onur Atakişi (ORCID: https://orcid.org/0000-0003-1183-6076)
- Kezban Yıldız-Dalgınlı
- Hatice Beşeren-Havadar
Institutions
- Kafkas University (TR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.80989.17525
- Primary Topic
- Humic Substances and Bio-Organic Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00