Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery.
Findings suggest that selegiline-loaded hydrogels can improve SCI through apoptosis inhibition and neurorescuing effects. Further clinical studies are warranted to validate these findings in human SCI.
Authors
- Mehri Farhang Ranjbar
- Maryam Baeeri (ORCID: https://orcid.org/0000-0002-5018-7438)
- Ramtin Farhadi
- Ramin Abrishami (ORCID: https://orcid.org/0000-0002-4380-6261)
- Seyed Hadi Aghili (ORCID: https://orcid.org/0009-0008-7525-3121)
Institutions
- Imam Khomeini Hospital (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
- Police Department (LT)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.81837.17706
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00