Comparative evaluation of biological and mechanical prostheses for aortic valve replacement in a middle-aged population: a population-based cohort study

Among middle-aged Asian patients undergoing AVR, biological and mechanical prostheses yield similar long-term survival, yet biological prostheses carry a lower risk of major adverse events, especially in those aged 55-64. Opting for biological prostheses at a younger age, potentially starting at age 55, may offer advantages in improving long-term outcomes.