Timing of anticoagulation restart after serious bleeding in atrial fibrillation
Restarting DOACs early after a serious bleeding event in AF patients may reduce stroke risk but is associated with an increased risk of recurrent bleeding. DOAC monotherapy appears to offer the best stroke protection, though with elevated bleeding risk. These findings highlight the need for individualised decision-making and further trials to define optimal timing for DOAC resumption.
Authors
- Nour R. Al‐Hussainy (ORCID: https://orcid.org/0000-0002-9118-206X)
- Gregory Y.H. Lip (ORCID: https://orcid.org/0000-0002-7566-1626)
- Manan Pareek (ORCID: https://orcid.org/0000-0002-0867-5825)
- Søren Lundbye‐Christensen (ORCID: https://orcid.org/0000-0002-9420-2783)
- Sam Riahi (ORCID: https://orcid.org/0000-0003-1849-9463)
- Kristian Hay Kragholm (ORCID: https://orcid.org/0000-0001-9629-8670)
- Christian Torp-Pedersen
- Susette Krohn Therkelsen
Institutions
- University of Liverpool (GB)
- Aalborg University Hospital (DK)
- Rigshospitalet (DK)
- Holbæk Sygehus (DK)
- Aalborg University (DK)
Publication Details
- Journal
- Heart
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1136/heartjnl-2024-325343
- Citations
- 1
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.39