Age differences in immunity to human seasonal coronaviruses and the immunogenicity of ChAdOx1 nCoV-19 (AZD1222)
The clinical trials COV002, COV003, COV004, and COV006 were made possible by funding from Astra Zeneca, the NIHR and the University of Oxford, UK Department of Health and Social Care, through the UK National Institute for Health and Care Research, the Wellcome Trust (220991), and Innovate UK (project 971614).
Authors
- Teresa Lambe (ORCID: https://orcid.org/0000-0001-7711-897X)
- Lily Yin Weckx (ORCID: https://orcid.org/0000-0003-4949-3582)
- Jordan R. Barrett (ORCID: https://orcid.org/0000-0003-0746-1945)
- Mark Harris (ORCID: https://orcid.org/0000-0002-9821-1003)
- Daisy Mugo (ORCID: https://orcid.org/0000-0003-3128-2461)
- Cameron Bissett (ORCID: https://orcid.org/0000-0003-3345-663X)
- Henry Karanja (ORCID: https://orcid.org/0000-0002-8249-6833)
- Daniel Wright (ORCID: https://orcid.org/0000-0002-8114-1838)
- Mainga Hamaluba (ORCID: https://orcid.org/0000-0002-0266-1414)
- An Yong
- Andrew J. Pollard (ORCID: https://orcid.org/0000-0001-7361-719X)
- Sagida Bibi (ORCID: https://orcid.org/0000-0002-0855-2737)
- R. H. Shaw (ORCID: https://orcid.org/0000-0003-3449-5876)
- John N. Gitonga (ORCID: https://orcid.org/0000-0001-6482-9107)
- Sandra Belij‐Rammerstorfer (ORCID: https://orcid.org/0000-0002-8637-3785)
- Nagendra Nath Barman (ORCID: https://orcid.org/0000-0001-9747-3426)
- Amy Flaxman (ORCID: https://orcid.org/0000-0001-6460-1372)
- Merryn Voysey (ORCID: https://orcid.org/0000-0001-6324-6559)
- Stanley Cheruiyot
- Khiyam Hussain (ORCID: https://orcid.org/0000-0002-6705-4412)
- George M. Warimwe (ORCID: https://orcid.org/0000-0002-4911-6333)
- Grace Li (ORCID: https://orcid.org/0000-0002-6661-0421)
- Holly Smith
- Gareth Lipunga (ORCID: https://orcid.org/0000-0001-9318-0124)
- Sue Ann Costa Clemens
- Emma Sheehan
- Susana Camara (ORCID: https://orcid.org/0000-0002-3154-5834)
Institutions
- University of Siena (IT)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Kenya Medical Research Institute (KE)
- University of Oxford (GB)
- Oxford BioMedica (United Kingdom) (GB)
- Science Oxford (GB)
- Jenner Institute (GB)
- Wellcome Trust (GB)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105847
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation
- AstraZeneca
- Wellcome Trust
- UK Research and Innovation
- Coalition for Epidemic Preparedness Innovations
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Oxford
- Chinese Academy of Medical Sciences
- Medical Research Council
- Engineering and Physical Sciences Research Council