Kartagener syndrome complicated by pulmonary tuberculosis, HIV, and hepatitis B: a rare case report

Abstract Kartagener syndrome is a rare autosomal recessive genetic disorder characterized by situs inversus, bronchiectasis, and sinusitis. This case report describes a 23-year-old male presenting with chronic cough, shortness of breath, and dextrocardia on CXR. HRCT confirmed situs inversus totalis and bronchiectasis. X-ray of PNS confirmed the presence of sinusitis, leading to the diagnosis of Kartagener syndrome. The patient also had coexisting hepatitis B, HIV, and pulmonary tuberculosis. The patient was managed with symptomatic treatment, antibiotics, ATT, ART, and antiviral therapy against hepatitis B. This case highlights the importance of considering Kartagener syndrome in patients with recurrent respiratory symptoms and situs inversus and the need for comprehensive evaluation and management of associated comorbidities.

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Publication Details

Journal
Egyptian Journal of Bronchology
Published
2025-07-16
DOI
https://doi.org/10.1186/s43168-025-00433-y
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
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article

Kartagener syndrome complicated by pulmonary tuberculosis, HIV, and hepatitis B: a rare case report

Tanusha Singh, Sunanda Haorongbam, Suchana Roy Bhowmik, Martina Thokchom
Egyptian Journal of Bronchology
Cystic Fibrosis Research Advances
article

Kartagener syndrome complicated by pulmonary tuberculosis, HIV, and hepatitis B: a rare case report

Tanusha Singh, Sunanda Haorongbam, Suchana Roy Bhowmik, Martina Thokchom
article en

Abstract

Abstract Kartagener syndrome is a rare autosomal recessive genetic disorder characterized by situs inversus, bronchiectasis, and sinusitis. This case report describes a 23-year-old male presenting with chronic cough, shortness of breath, and dextrocardia on CXR. HRCT confirmed situs inversus totalis and bronchiectasis. X-ray of PNS confirmed the presence of sinusitis, leading to the diagnosis of Kartagener syndrome. The patient also had coexisting hepatitis B, HIV, and pulmonary tuberculosis. The patient was managed with symptomatic treatment, antibiotics, ATT, ART, and antiviral therapy against hepatitis B. This case highlights the importance of considering Kartagener syndrome in patients with recurrent respiratory symptoms and situs inversus and the need for comprehensive evaluation and management of associated comorbidities.

Egyptian Journal of BronchologyVol. 19(1)
Regional Institute of Medical Sciences (IN)
Openalex Percentile: Top 72%
Cystic Fibrosis Research Advances
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