On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death
Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant deaths in this population. Donation after circulatory death (DCD) with normothermic regional perfusion has the potential to increase the donor pool by up to 30%. Ethical concerns have limited adoption of this technique in the United States and abroad. Consequently, a method facilitating ex vivo resuscitation of hearts from deceased donors after circulatory death (i.e., DCD hearts) is needed. We describe an on-table reanimation of a pediatric DCD heart transplanted into a 3-month-old recipient. Adverse events are reported.
Authors
- Joseph William Turek (ORCID: https://orcid.org/0000-0002-4006-7555)
- Douglas M. Overbey (ORCID: https://orcid.org/0000-0003-2343-7240)
- John A. Kucera
Institutions
- Duke University (US)
- Duke Children's Hospital & Health Center (US)
- Duke University Hospital (US)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1056/nejmoa2503487
- Citations
- 11
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 24.79