GPC3: a novel mutated gene in pleuropulmonary blastoma
Our findings propose GPC3 as a novel mutation contributing to PPB susceptibility and progression. Elevated GPC3 expression correlates with poorer survival outcomes, indicating its potential as a prognostic marker and therapeutic target in PPB management.
Authors
- Yu‐Ying He (ORCID: https://orcid.org/0000-0002-2665-7962)
- Jiahang Zeng (ORCID: https://orcid.org/0000-0002-0370-2492)
- Jue Tang (ORCID: https://orcid.org/0000-0002-3765-277X)
- Yingyi Xu (ORCID: https://orcid.org/0000-0001-8335-9198)
- Dongmei Huang (ORCID: https://orcid.org/0000-0002-5412-4063)
- Liang Li (ORCID: https://orcid.org/0000-0001-9139-5025)
- Linkai Huang (ORCID: https://orcid.org/0000-0001-7810-4852)
- Fenghua Wang (ORCID: https://orcid.org/0000-0002-2443-8360)
- Xinying Wang (ORCID: https://orcid.org/0000-0002-6663-9232)
- Zefeng Lin (ORCID: https://orcid.org/0000-0001-7532-9175)
- Qinglin Yang (ORCID: https://orcid.org/0000-0003-2397-7327)
- Jianhua Liang (ORCID: https://orcid.org/0000-0002-6162-3717)
- Junzheng Peng (ORCID: https://orcid.org/0000-0001-9263-3347)
- Jiachi Liao
Institutions
- Guangzhou Women and Children Medical Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1007/s12672-025-02937-x
- Primary Topic
- Congenital Diaphragmatic Hernia Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China