Endoscopic diamond magnetometer for cancer surgery

Intraoperative measurements using magnetic sensors are a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy center magnetometer capable of detecting iron oxide suspension (MagTrace™ from Endomagnetics Ltd.) used in breast cancer surgeries. Detection of an iron mass as low as 0.56 mg has been demonstrated, 100 times less than that of a recommended dose at a maximum distance of 5.8 mm. Detection of an iron concentration as low as 2.8 mg/ml has also been demonstrated, 20 times less than a recommended dose. The maximum working distance from the sensor can be as large as 14.6 mm for higher concentrations. The sensor head has a maximum diameter of 10 mm which would allow it to be used for endoscopy, laparoscopy, and intraoperative surgery.

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Publication Details

Journal
Physical Review Applied
Published
2025-07-16
DOI
https://doi.org/10.1103/znt3-988w
Citations
2
Primary Topic
Atomic and Subatomic Physics Research
Type
article
Field-Weighted Citation Impact
2.49

Funders

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article

Endoscopic diamond magnetometer for cancer surgery

Gavin W. Morley, Matthew Markham, Colin Stephen, Suzanne Graham et al.
2 citations
Physical Review Applied
Atomic and Subatomic Physics Research
2.49
article

Endoscopic diamond magnetometer for cancer surgery

Gavin W. Morley, Matthew Markham, Colin Stephen, Suzanne Graham, Andrew M. Edmonds, Karl J. Friston
article en
2 citations

Abstract

Intraoperative measurements using magnetic sensors are a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy center magnetometer capable of detecting iron oxide suspension (MagTrace™ from Endomagnetics Ltd.) used in breast cancer surgeries. Detection of an iron mass as low as 0.56 mg has been demonstrated, 100 times less than that of a recommended dose at a maximum distance of 5.8 mm. Detection of an iron concentration as low as 2.8 mg/ml has also been demonstrated, 20 times less than a recommended dose. The maximum working distance from the sensor can be as large as 14.6 mm for higher concentrations. The sensor head has a maximum diameter of 10 mm which would allow it to be used for endoscopy, laparoscopy, and intraoperative surgery.

Physical Review AppliedVol. 24(2)
Engineering and Physical Sciences Research Council (GB), University of Warwick (GB), Element Six (United Kingdom) (GB)
University Hospitals Coventry and Warwickshire NHS Trust, Defence Science and Technology Laboratory, Engineering and Physical Sciences Research Council, Defence Science and Technology Group
Good health and well-being
Openalex Percentile: Top 11%
Atomic and Subatomic Physics Research
2.49
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