Serial extracellular volume quantification using cardiac magnetic resonance imaging in transthyretin amyloidosis patients treated with tafamidis
Question What is the prognostic significance of serial ECV quantification in transthyretin amyloidosis patients on tafamidis treatment? Findings Change of ECV is a strong predictor of a combined endpoint consisting of all-cause mortality, cardiac transplantation, or hospitalization due to HF. Clinical relevance Patients with increasing ECV might potentially benefit from a change in amyloid-specific treatment to a different agent.
Authors
- Luciana Camuz-Ligios
- Hermine Agis (ORCID: https://orcid.org/0000-0002-1125-0211)
- Christian Loewe (ORCID: https://orcid.org/0000-0003-2502-0676)
- Carolina Donà (ORCID: https://orcid.org/0000-0002-6723-005X)
- Johannes Kästner (ORCID: https://orcid.org/0000-0001-6178-7669)
- Franz Duca (ORCID: https://orcid.org/0000-0002-7519-5274)
- Christina Binder (ORCID: https://orcid.org/0000-0001-6060-7910)
- Michael Poledniczek (ORCID: https://orcid.org/0000-0002-6091-9823)
- Matthias Koschutnik (ORCID: https://orcid.org/0000-0001-6164-8773)
- Jutta K Bergler-Klein (ORCID: https://orcid.org/0000-0003-2591-1380)
- Christina Kronberger (ORCID: https://orcid.org/0000-0002-3866-3710)
- René Rettl (ORCID: https://orcid.org/0000-0001-6409-5158)
- Andreas Anselm Kammerlander (ORCID: https://orcid.org/0000-0002-7632-9879)
- R Badr-Eslam
- Dietrich Beitzke (ORCID: https://orcid.org/0009-0003-2573-9426)
- Christian Hengstenberg
- Christian Nitsche
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- European Radiology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1007/s00330-025-11792-x
- Citations
- 1
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.81