Racial and ethnic differences in epigenetic aging: The National Health and Nutrition Examination Survey, 1999–2002
White respondents had higher epigenetic aging than Black respondents for measures trained on chronological age, whereas the opposite was true for measures trained on physiological age. More work is needed to validate measures of epigenetic aging in non-White populations and to determine whether these measures are associated with health-related outcomes similarly across racial and ethnic groups.
Authors
- Nicole Gladish (ORCID: https://orcid.org/0000-0001-6039-7001)
- Belinda L. Needham (ORCID: https://orcid.org/0000-0001-5939-2027)
- Xiang Zhou (ORCID: https://orcid.org/0000-0002-4331-7599)
- Jennifer A. Smith (ORCID: https://orcid.org/0000-0002-3575-5468)
- Hanyang Shen (ORCID: https://orcid.org/0000-0003-3273-9777)
- David H. Rehkopf (ORCID: https://orcid.org/0000-0002-7597-6513)
- Bhramar Mukherjee (ORCID: https://orcid.org/0000-0003-0118-4561)
- Ching‐Ti Liu (ORCID: https://orcid.org/0000-0002-0703-0742)
Institutions
- Duke University (US)
- University of Michigan (US)
- Yale University (US)
- Stanford Health Care (US)
- Michigan United (US)
- Duke University Hospital (US)
- Stanford University (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1371/journal.pone.0327010
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Institute on Minority Health and Health Disparities