Quorum quenching by Est816: a novel approach to control Porphyromonas gingivalis pathogenicity
Est816 exhibited anti-biofilm property, attenuated virulence release in P. gingivalis, and counteracted AHL-mediated suppression of osteoblast differentiation in PDLSCs, highlighting its dual therapeutic role in both pathogen inhibition and host tissue regeneration for peri-implantitis.
Authors
- Tianfan Cheng (ORCID: https://orcid.org/0000-0002-3212-6228)
- Xiangyang Li (ORCID: https://orcid.org/0009-0001-3360-7381)
- Lifeng Guo
- Ziyi Zhao (ORCID: https://orcid.org/0000-0001-7804-0537)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-7650-4702)
Institutions
- Anhui Medical University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s12903-025-06563-5
- Citations
- 1
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 1.47