Impact of left atrial anatomy on pulmonary vein isolation with cryoballoon ablation: Insights from the randomized controlled COMPARE CRYO study
The absence of an orthogonal orientation of the left-sided PVs was significantly associated with lower first-pass isolation rates and a higher risk of recurrence. These findings highlight the importance of preprocedural anatomical assessment to identify potential challenges and tailor ablation strategies.
Authors
- Philipp Krisai (ORCID: https://orcid.org/0000-0002-4367-2363)
- Laurent Roten (ORCID: https://orcid.org/0000-0002-0827-1329)
- Thomas Kueffer (ORCID: https://orcid.org/0000-0003-3553-4945)
- Helge Servatius (ORCID: https://orcid.org/0000-0003-2887-8707)
- Behnam Subin (ORCID: https://orcid.org/0000-0002-4997-9841)
- Maurice Pradella (ORCID: https://orcid.org/0000-0003-2449-7835)
- Felix Mahfoud (ORCID: https://orcid.org/0000-0002-4425-549X)
- Salik ur Rehman Iqbal (ORCID: https://orcid.org/0000-0001-6361-1130)
- Nicolas Schärli
- Gregor Thalmann (ORCID: https://orcid.org/0000-0002-2050-6311)
- Vincent Schlageter (ORCID: https://orcid.org/0000-0001-6305-5103)
- Michael Kühne (ORCID: https://orcid.org/0000-0002-2937-3711)
- Beat Schaer (ORCID: https://orcid.org/0000-0003-1768-1968)
- Patrick Badertscher (ORCID: https://orcid.org/0000-0001-9751-0557)
- Jens Maurhofer (ORCID: https://orcid.org/0000-0003-4442-8941)
- Sven Knecht (ORCID: https://orcid.org/0000-0001-7122-021X)
- Hildegard Tanner (ORCID: https://orcid.org/0000-0001-9722-5617)
- Christian Sticherling (ORCID: https://orcid.org/0000-0001-8428-7050)
- Corinne Isenegger
- Corinne Jufer
- David Spreen
- Tobias Reichlin
Institutions
- University Hospital of Bern (CH)
- University Hospital of Basel (CH)
Publication Details
- Journal
- Heart Rhythm O2
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1016/j.hroo.2025.07.005
- Citations
- 1
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Science Foundation
- Pfizer
- Foundation for Cardiovascular Research
- Universität Basel
- Boston Scientific Corporation
- ReCor Medical
- European Commission
- Deutsche Forschungsgemeinschaft
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Schweizerische Herzstiftung
- Universität des Saarlandes
- Deutsche Herzstiftung
- MicroPort
- Biosense Webster
- Daiichi Sankyo Europe