Precision Treatment of Cryptogenic Brain Abscesses: Metagenomic Next-generation Sequencing and Imaging for Recurrence Control

Combined multimodal imaging and mNGS serve as the core modalities for early diagnosis of cryptogenic brain abscesses. Surgical resection significantly improves cure rates and reduces recurrence risk, particularly suitable for patients with abscesses larger than 2.5 cm in diameter or mixed infections.

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Publication Details

Journal
World Neurosurgery
Published
2025-07-16
DOI
https://doi.org/10.1016/j.wneu.2025.124288
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Precision Treatment of Cryptogenic Brain Abscesses: Metagenomic Next-generation Sequencing and Imaging for Recurrence Control

Xiaoyu Zheng, Maoying Zhang, Dongyue Li, Menghui Li et al.
World Neurosurgery
Bacterial Infections and Vaccines
article

Precision Treatment of Cryptogenic Brain Abscesses: Metagenomic Next-generation Sequencing and Imaging for Recurrence Control

Xiaoyu Zheng, Maoying Zhang, Dongyue Li, Menghui Li, Jian-Cheng Liao
article en

Abstract

Combined multimodal imaging and mNGS serve as the core modalities for early diagnosis of cryptogenic brain abscesses. Surgical resection significantly improves cure rates and reduces recurrence risk, particularly suitable for patients with abscesses larger than 2.5 cm in diameter or mixed infections.

World NeurosurgeryVol. 201
First Affiliated Hospital of Jinan University (CN)
Zero hunger
Openalex Percentile: Top 84%
Bacterial Infections and Vaccines
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