Clinical Outcome of Febrile Neutropenia and Associated Factors Among Adult Patients with Cancer Treated at Ethiopian Oncology Centers: A Retrospective Observational Study
The 30-day all-cause mortality rate was high among patients with FN. Old age, low MASCC score, hypoalbuminemia, lymphopenia, and elevated GGT levels were found to be significantly associated with 30-day all-cause mortality. Healthcare providers should consider these factors in order to manage and mitigate the risks associated with the 30-day all-cause mortality. Further prospective studies are warranted to confirm our results and identify therapeutic strategies that can improve survival.
Authors
- Fasil Bayafers Tamene (ORCID: https://orcid.org/0009-0005-3026-6584)
- Mekdes Kiflu (ORCID: https://orcid.org/0000-0001-5387-8253)
- Eyayaw Ashete Belachew (ORCID: https://orcid.org/0000-0002-0421-4327)
- Samuel Agegnew Wondm (ORCID: https://orcid.org/0000-0002-0723-6804)
- Getachew Yitayew Tarekegn (ORCID: https://orcid.org/0000-0002-8678-6723)
- Tilaye Arega Moges (ORCID: https://orcid.org/0000-0001-6813-8792)
- Bantayehu Addis Tegegne (ORCID: https://orcid.org/0000-0002-6178-8335)
- Wubetu Yihunie Belay (ORCID: https://orcid.org/0000-0003-2703-8941)
- Ashenafi Kibret Sendekie (ORCID: https://orcid.org/0000-0001-5982-853X)
- Samuel Berihun Dagnew (ORCID: https://orcid.org/0000-0002-8938-4551)
- Tirsit Ketsela Zeleke (ORCID: https://orcid.org/0000-0003-3528-0703)
- Fisseha Nigussie Dagnew (ORCID: https://orcid.org/0009-0001-3309-9102)
Institutions
- Curtin University (AU)
- Debre Tabor University (ET)
- University of Gondar (ET)
- Debre Markos University (ET)
Publication Details
- Journal
- Oncology and Therapy
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1007/s40487-025-00356-0
- Citations
- 6
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 6.27