Exploring biological neuronal correlations with quantum generative models

<h2>Summary</h2> Understanding how biological neural networks process information is one of the biggest open scientific questions of our time. Advances in machine learning and artificial neural networks have enabled the modeling of neuronal behavior, but classical models often require a large number of parameters and highly task-specific architectures, which can complicate model design and scalability. Quantum computing offers an alternative approach through quantum machine learning, which can achieve efficient training with fewer parameters. In this work, we introduce a quantum generative model framework for generating synthetic data that captures the spatial and temporal correlations of biological neuronal activity. Our model demonstrates the ability to achieve reliable outcomes with fewer trainable parameters compared to classical methods. These findings highlight the potential of quantum generative models to provide new tools for modeling and understanding neuronal behavior, offering a promising avenue for future research in neuroscience.

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Publication Details

Journal
Cell Reports Physical Science
Published
2025-07-16
DOI
https://doi.org/10.1016/j.xcrp.2025.102682
Citations
1
Primary Topic
Neural dynamics and brain function
Type
article
Field-Weighted Citation Impact
1.43

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article

Exploring biological neuronal correlations with quantum generative models

Vinicius Hernandes, Eliška Greplová
1 citations
Cell Reports Physical Science
Neural dynamics and brain function
1.43
article

Exploring biological neuronal correlations with quantum generative models

Vinicius Hernandes, Eliška Greplová
article en
1 citations

Abstract

<h2>Summary</h2> Understanding how biological neural networks process information is one of the biggest open scientific questions of our time. Advances in machine learning and artificial neural networks have enabled the modeling of neuronal behavior, but classical models often require a large number of parameters and highly task-specific architectures, which can complicate model design and scalability. Quantum computing offers an alternative approach through quantum machine learning, which can achieve efficient training with fewer parameters. In this work, we introduce a quantum generative model framework for generating synthetic data that captures the spatial and temporal correlations of biological neuronal activity. Our model demonstrates the ability to achieve reliable outcomes with fewer trainable parameters compared to classical methods. These findings highlight the potential of quantum generative models to provide new tools for modeling and understanding neuronal behavior, offering a promising avenue for future research in neuroscience.

Cell Reports Physical ScienceVol. 6(8)
QuTech (NL), Delft University of Technology (NL)
Kavli Foundation, Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Openalex Percentile: Top 17%
Neural dynamics and brain function
1.43
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