Associations of early pregnancy high-sensitivity C-reactive protein levels with subsequent gestational diabetes: A Finnish gestational diabetes study
Early pregnancy serum hsCRP levels were associated with subsequent gestational diabetes, and most with a higher number of abnormal values and postprandial hyperglycemia in the oral glucose tolerance test. These findings highlight the role of chronic inflammation and clustering of metabolic risk factors involved in gestational diabetes and its severity.
Authors
- Elina Keikkala (ORCID: https://orcid.org/0000-0002-4401-213X)
- Eero Kajantie (ORCID: https://orcid.org/0000-0001-7081-8391)
- Shilpa Lingaiah (ORCID: https://orcid.org/0000-0003-0005-9187)
- Hanna Öhman (ORCID: https://orcid.org/0000-0003-4973-9167)
- Sanna Mustaniemi (ORCID: https://orcid.org/0000-0003-4483-830X)
- Marja Vääräsmäki (ORCID: https://orcid.org/0000-0002-8234-4434)
Institutions
- University of Helsinki (FI)
- Norwegian University of Science and Technology (NO)
- Oulu University Hospital (FI)
- Helsinki University Hospital (FI)
- Finnish Institute for Health and Welfare (FI)
- Borealis (Finland) (FI)
- University of Oulu (FI)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s13098-025-01843-0
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Suomen Lääketieteen Säätiö
- Yrjö Jahnssonin Säätiö
- Juho Vainion Säätiö
- Novo Nordisk
- Signe ja Ane Gyllenbergin Säätiö
- Lastentautien Tutkimussäätiö
- Oulun Yliopisto
- Sigrid Juséliuksen Säätiö