Synergistic effects of NF-κB1 and inflammatory pathway polymorphisms on hypertension and dyslipidemia susceptibility in type 2 diabetes
This study establishes that genetic variants in inflammatory pathways (TLR9, NF-κB1, IL6R) synergistically drive hypertension and dyslipidemia risks in T2DM.
Authors
- Jing Qiu Cheng (ORCID: https://orcid.org/0000-0001-7100-1180)
- Hailian Chen
- Mengna Guo (ORCID: https://orcid.org/0000-0003-1480-0474)
- Chao Zuo (ORCID: https://orcid.org/0000-0002-1461-0032)
- Dongli Yang (ORCID: https://orcid.org/0000-0001-5026-3149)
- Yi Liu (ORCID: https://orcid.org/0000-0001-8451-6079)
- Ziqiang Wang (ORCID: https://orcid.org/0000-0002-4676-3447)
- Yu Wang
- Zhuo Yang (ORCID: https://orcid.org/0000-0002-5296-8596)
- Xiang Lü (ORCID: https://orcid.org/0000-0001-8351-1778)
- Yongchao Qiao (ORCID: https://orcid.org/0000-0002-2902-9566)
Institutions
- Bengbu Medical College (CN)
- Guilin Medical University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s13098-025-01861-y
- Citations
- 2
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Natural Science Foundation of Guangxi Province
- Division of Graduate Education