Functional Gonadotroph Adenomas in Male Patients: Clinical Characteristics, Surgical Outcomes, and Hormonal Follow-up
All patients presented with elevated FSH levels, and a minority also had elevated LH or low testosterone. Surgery led to a reduction in symptomatic complaints in many cases, and the majority achieved gross total resection. Given that most patients continue to exhibit hormonal abnormalities postoperatively, close follow-up and thorough investigation of gonadal dysfunction is essential, as many patients may require ongoing medical management.
Authors
- Ivan H. El‐Sayed (ORCID: https://orcid.org/0000-0001-8121-3726)
- Jacob S. Young (ORCID: https://orcid.org/0000-0002-5499-4325)
- Lewis S. Blevins
- Zain Peeran (ORCID: https://orcid.org/0000-0003-1959-7321)
- Aarav Badani
- Miguel Alejandro Jiménez Pérez
- Mulki Mehari
- Philip V. Theodosopoulos (ORCID: https://orcid.org/0000-0002-8311-4729)
- Manish K. Aghi (ORCID: https://orcid.org/0000-0002-2949-2227)
- José Gurrola (ORCID: https://orcid.org/0000-0001-6801-5768)
- Robert C. Osorio (ORCID: https://orcid.org/0000-0002-7669-2176)
- Harmon Singh Khela (ORCID: https://orcid.org/0000-0002-1962-3844)
- Abraham Dada (ORCID: https://orcid.org/0000-0002-2125-7011)
- Aymen Kabir
- Sandeep Kunwar
Institutions
- University of California, San Francisco (US)
- Wellcome Sanger Institute (GB)
- University of California San Francisco Medical Center (US)
- Neurological Surgery (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Operative Neurosurgery
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1227/ons.0000000000001693
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00