XBB.1.5 COVID-19 mRNA Vaccines Induce Inadequate Mucosal Immunity in Patients with Inflammatory Bowel Disease
Since mucosal IgA plays a pivotal role in infection control, the lack of IgA induction indicates that patients lack sufficient protection against SARS-CoV-2 infections which warrants the development of mucosal COVID-19 vaccines.
Authors
- Wolfgang Korte (ORCID: https://orcid.org/0000-0003-0076-5022)
- Werner C. Albrich (ORCID: https://orcid.org/0000-0003-0607-7159)
- J.J. Burgi (ORCID: https://orcid.org/0000-0003-4210-0061)
- Marius König
- Daniel Junker (ORCID: https://orcid.org/0000-0002-5331-3479)
- Nicole Schneiderhan‐Marra (ORCID: https://orcid.org/0000-0001-6785-181X)
- Samuel Truniger (ORCID: https://orcid.org/0000-0002-5708-0975)
- Matthias Friedrich (ORCID: https://orcid.org/0000-0002-7551-4853)
- Claudia Krieger‐Grübel (ORCID: https://orcid.org/0000-0002-7949-0385)
- Nicola Frei (ORCID: https://orcid.org/0000-0002-5358-2767)
- Jan Hendrik Niess (ORCID: https://orcid.org/0000-0001-6902-5650)
- Annett Franke
- Seraina Koller
- Simon Woelfel (ORCID: https://orcid.org/0000-0003-2528-0582)
- Stephan Brand (ORCID: https://orcid.org/0000-0001-7011-0430)
- Joel Dütschler
- Alex Dulovic (ORCID: https://orcid.org/0000-0003-0017-6738)
- Georg Leinenkugel
- Katline Metzger‐Peter
Institutions
- University of Basel (CH)
- University of St.Gallen (CH)
- University Hospital of Basel (CH)
- University of Oxford (GB)
- Natural and Medical Sciences Institute (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- Hochschule für Logopädie Ostschweiz (CH)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Vaccines
- Published
- 2025-07-16
- DOI
- https://doi.org/10.3390/vaccines13070759
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Oxford
- HORIZON EUROPE Framework Programme
- HORIZON EUROPE European Research Council