Suspected statin-related adverse drug reactions: analysis of spontaneous reports in Hubei Province, China (2014–2022)
Atorvastatin was associated with a higher number of ADR reports and a higher proportion of serious ADRs than the other statins. Atorvastatin may cause off-label ADRs such as back pain, increased blood bilirubin, bone pain, hemorrhage, hepatic failure, and hepatocellular injury. Drug instructions should be enriched for better labeling of ADRs.
Authors
- H.-X. Wang (ORCID: https://orcid.org/0009-0006-9480-7842)
- Xianglong Chen
- Hongyun Bi (ORCID: https://orcid.org/0000-0002-8739-8634)
- Yuanxuan Cai
- Rui Huang (ORCID: https://orcid.org/0000-0003-4124-3896)
- Zherui Chen
- Xiaofang Shangguan
Institutions
- Zhongnan University of Economics and Law (CN)
- Henan Provincial Health Bureau (CN)
- Wuhan University of Science and Technology (CN)
- Huazhong University of Science and Technology (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Expert Opinion on Drug Safety
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1080/14740338.2025.2536343
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China