Iminosugars of the Invasive Arboreal Amorpha fruticosa and Glycosidase Inhibition Potential

<i>A. fruticosa</i> pods and leaves were found to contain a number of compounds that could contribute to the potential antihyperglycemic activities including pinitol and a complex mixture of iminosugar-related compounds derived from pipecolic acids and prolines. The pods and leaves caused potent selective inhibition of glucosidases and hexosaminidases and beta-glucuronidase. The variation between the collections might reflect the sites differing or wide phenotypic versatility allowing the success of the species as an invasive plant.

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Publication Details

Journal
Plants
Published
2025-07-16
DOI
https://doi.org/10.3390/plants14142205
Primary Topic
Carbohydrate Chemistry and Synthesis
Type
article
Field-Weighted Citation Impact
0.00

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article

Iminosugars of the Invasive Arboreal Amorpha fruticosa and Glycosidase Inhibition Potential

Ekaterina Kozuharova, Yana B. Penkova, Robert J. Nash, Barbara Bartholomew
Plants
Carbohydrate Chemistry and Synthesis
article

Iminosugars of the Invasive Arboreal Amorpha fruticosa and Glycosidase Inhibition Potential

Ekaterina Kozuharova, Yana B. Penkova, Robert J. Nash, Barbara Bartholomew
article en

Abstract

<i>A. fruticosa</i> pods and leaves were found to contain a number of compounds that could contribute to the potential antihyperglycemic activities including pinitol and a complex mixture of iminosugar-related compounds derived from pipecolic acids and prolines. The pods and leaves caused potent selective inhibition of glucosidases and hexosaminidases and beta-glucuronidase. The variation between the collections might reflect the sites differing or wide phenotypic versatility allowing the success of the species as an invasive plant.

PlantsVol. 14(14)
Aberystwyth University (GB), Medical University of Sofia (BG)
European Commission
Life in Land
Openalex Percentile: Top 87%
Carbohydrate Chemistry and Synthesis
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