Verteporfin attenuates NLRP3 inflammasome activation to alleviate gout arthritis flares
Collectively, these data suggest verteporfin is a NLRP3 inflammasome inhibitor that could be repurposed as a treatment for GA.
Authors
- Tyler K. Ulland
- Daniel C. Shippy
Institutions
- University of Wisconsin–Madison (US)
Publication Details
- Journal
- Journal of Inflammation
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s12950-025-00455-9
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- William F. Vilas Trust Estate
- National Institutes of Health