Imatinib prevents blood-spinal cord barrier disruption by inhibiting PDGFR-mediated JMJD3 expression and activation after spinal cord injury
Based on these findings, we propose that imatinib exerts a neuroprotective effect, in part by inhibiting PDGFR-mediated JMJD3 expression and activation following SCI.
Authors
- Tae Young Yune (ORCID: https://orcid.org/0000-0001-5242-5746)
- Jee Youn Lee (ORCID: https://orcid.org/0000-0003-0435-0756)
- Chan Sol Park (ORCID: https://orcid.org/0000-0001-6294-3854)
Institutions
- Kyung Hee University (KR)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s12987-025-00690-5
- Citations
- 4
- Primary Topic
- Spinal Hematomas and Complications
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea