Effect of lacosamide on cortical spreading depolarization in mice
In female mice, single dose LCM treatment significantly reduced CSD frequency induced by KCl. Further investigations are warranted to assess the clinical potential of LCM in preventing migraine.
Authors
- Tsubasa Takizawa (ORCID: https://orcid.org/0000-0003-2605-7200)
- Yoshikane Izawa (ORCID: https://orcid.org/0000-0001-9416-4660)
- Jin Nakahara (ORCID: https://orcid.org/0000-0002-5858-0998)
- Keiko Ihara (ORCID: https://orcid.org/0000-0001-5644-0468)
- Chisato Iba
- Miyuki Unekawa (ORCID: https://orcid.org/0000-0003-2653-6121)
Institutions
- Keio University (JP)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s10194-025-02099-9
- Citations
- 1
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Japan Society for the Promotion of Science