Promucetin, a new C-type lectin-like protein modulates coagulation by activating platelets via GPIb
Promucetin exhibits significant ability to modulate coagulation function and effectively inhibit thrombosis by activating platelet via GPIb and reducing platelet count, which helps us understand its biological function in snake bites, it exhibits the potential to be a candidate for anticoagulant therapy.
Authors
- Shuting Zhou
- Qian‐Yun Sun (ORCID: https://orcid.org/0000-0001-9691-2028)
- Qing‐Yu Lu
- Qi-Yun Zhang
- Xiaoqin Yu
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences (CN)
Publication Details
- Journal
- The Journal of venomous animals and toxins including tropical diseases
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1678-9199-jvatitd-2025-0003
- Primary Topic
- Biochemical and Structural Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.00