Bacteriological profile and antimicrobial resistance in sepsis cases in intensive care units in Lubumbashi: challenges and perspectives
This study highlights the high prevalence of Gram-negative bacteria and concerning resistance to first-line antibiotics, jeopardizing the effectiveness of empirical treatments. These findings underscore the urgency of strengthening microbiological surveillance, rationalizing antibiotic use, and implementing antimicrobial resistance control policies in the DRC. Developing treatment protocols tailored to local data and enforcing stricter antibiotic regulations are essential to improving sepsis management and reducing associated mortality.
Authors
- Christian Kakisingi (ORCID: https://orcid.org/0000-0003-4907-3190)
- Serge Kapend Matanda
- Rivain Fefe Iteke
- Michel Muteya Manika (ORCID: https://orcid.org/0000-0002-2344-2472)
- Kasamba Ilunga Éric (ORCID: https://orcid.org/0000-0001-6665-7265)
- Berthe Barhayiga
- Claude Mulumba Mwamba
- Hippolyte Nani-Tuma Situakibanza
- Liévin Kalala Kapend’a
- Aristophane Koffi Tano
- Albert Tambwe A Nkoy Mwembo
- Floreance Mutomb Mujing'a
- Ildéphonse Wa Mwanza Teta
- Yves Banza Mukalay
Institutions
- University of Lubumbashi (CD)
- University of Kinshasa (CD)
- Université Félix Houphouët-Boigny (CI)
Publication Details
- Journal
- Annals of Clinical Microbiology and Antimicrobials
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s12941-025-00811-w
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35