Quantitative study of changes in the hippocampus after whole-brain radiotherapy via multisequence magnetic resonance imaging radiomics
Compared with volume, multisequence MRI radiomics features more directly reflect dynamic microscopic hippocampal changes across MRI<sub>pre</sub>, MRI<sub>post</sub>, and MRI<sub>follow</sub> time points. T2WI and T1WI captured early sustained radiomics alterations, whereas CE-T1WI reflected delayed changes, thus serving as potential biomarkers for the monitoring of hippocampal dynamics following WBRT.
Authors
- Shanshan Du (ORCID: https://orcid.org/0000-0001-6889-116X)
- Guanzhong Gong (ORCID: https://orcid.org/0000-0002-4943-8084)
- Rui Liu (ORCID: https://orcid.org/0000-0002-7998-0034)
- Yong Yin (ORCID: https://orcid.org/0000-0003-2321-9200)
- Ruozheng Wang (ORCID: https://orcid.org/0000-0003-0127-4436)
- Kangning Meng
Institutions
- Xinjiang Medical University (CN)
- Tumor Hospital of Xinjiang Medical University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111461
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Taishan Scholar Foundation of Shandong Province