Early acetaminophen administration and mortality outcomes in critically ill patients with cirrhosis: a retrospective analysis from the MIMIC-IV database
Early APAP administration in critically ill cirrhotic patients is associated with increased mortality. These findings underscore the need for caution when prescribing APAP in this high-risk population and highlight the importance of further prospective validation.
Authors
- Shenao Fu
- Lu Wen (ORCID: https://orcid.org/0000-0002-1773-1876)
- Xuan He (ORCID: https://orcid.org/0000-0003-2662-7613)
- Ji‐Tseng Fang (ORCID: https://orcid.org/0000-0002-9223-7106)
- Na Guo (ORCID: https://orcid.org/0000-0002-3350-0349)
- Xiaofei Fan (ORCID: https://orcid.org/0000-0003-2730-3311)
- Sanzhang Xu (ORCID: https://orcid.org/0009-0003-4695-554X)
Institutions
- Central South University (CN)
- Second Hospital of Shandong University (CN)
- Third Xiangya Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1186/s12876-025-04113-5
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Massachusetts Institute of Technology