DNA-incorporated thioguanine to detect potential non-adherence to maintenance therapy in acute lymphoblastic leukemia
DNA-TG can provide a cost-effective guidance on when to measure TGN and MeMP to determine whether non-adherence should be suspected, which is an additional benefit to monitoring DNA-TG during maintenance therapy.
Authors
- Jacob Nersting (ORCID: https://orcid.org/0000-0001-9144-7972)
- M. Koch
- Inge M. van der Sluis (ORCID: https://orcid.org/0000-0002-5822-7668)
- Gabriele Escherich (ORCID: https://orcid.org/0000-0003-2167-3805)
- Maria Thastrup (ORCID: https://orcid.org/0000-0001-9950-5911)
- Mats Heyman (ORCID: https://orcid.org/0000-0001-7637-1949)
- Heidi Segers (ORCID: https://orcid.org/0000-0002-3604-7850)
- Riitta Niinimäki (ORCID: https://orcid.org/0000-0003-0190-5664)
- Ximo Duarte (ORCID: https://orcid.org/0000-0001-5332-0284)
- Linea Natalie Toksvang (ORCID: https://orcid.org/0000-0002-9871-7637)
- Johan Malmros (ORCID: https://orcid.org/0000-0002-7274-2957)
- Malene Johanne Petersen (ORCID: https://orcid.org/0000-0002-0531-8531)
- Annie Rasmussen (ORCID: https://orcid.org/0000-0002-4997-2914)
- Bodil Als‐Nielsen
- Inga María Jóhannsdóttir (ORCID: https://orcid.org/0000-0002-2340-6041)
- Kjeld Schmiegelow (ORCID: https://orcid.org/0000-0002-0829-4993)
- Goda Vaitkevičienė (ORCID: https://orcid.org/0000-0001-6724-8164)
- Kristi Lepik
Institutions
- University of Copenhagen (DK)
- Oslo University Hospital (NO)
- Karolinska University Hospital (SE)
- Universität Hamburg (DE)
- Vilnius University (LT)
- Oulu University Hospital (FI)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- University Medical Center Hamburg-Eppendorf (DE)
- Tallinn Health Care College (EE)
- Princess Máxima Center (NL)
- Instituto Português de Oncologia de Coimbra Francisco Gentil (PT)
- Catholic University of America (US)
- KU Leuven (BE)
Publication Details
- Journal
- Cancer Chemotherapy and Pharmacology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.1007/s00280-025-04784-7
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Dagmar Marshalls Fond
- Børnecancerfonden
- Vissing Fonden