Early Detection of Pulmonary Hypertension in Pediatric Sickle Cell Anemia: A Non-invasive Diagnostic Approach

What is known on this subject?Pulmonary hypertension (PH) represents a progressive and often subclinical complication in pediatric sickle cell anemia (SCA), for which non-invasive modalities such as Doppler echocardiography and biomarker assessment provide valuable tools for early risk stratification and clinical surveillance. What this study adds?This study provides evidence supporting the implementation of non-invasive screening modalities, including echocardiographic parameters and laboratory biomarkers, for early identification of PH in children with SCA.