LOCALIZE SCROTAL KAPOSI SARCOMA IN A HIV-NEGATIVE PATIENT

Kaposi sarcoma (KS) is an endothelial originated angio-proliferative disease. There are four main types of KS; classic, endemic, iatrogenic (transplantation associated KS) and HIV-associated. Even if the disease mostly occurs in mucocutaneous sites; face, trunk, the skin of the lower extremities, and genitalia frequently involved. Even KS is mostly seen in the penis in the urogenital system, the scrotal disease is rare. A 68-year-old male was admitted to the dermatology clinic with blue-purple lesions on the scrotum. He was referred to our medical oncology clinic when tissue biopsy was resulted as ‘Classical Kaposi Sarcoma’. His serologic test was negative for HIV Human Herpes Virus but (HHV-8) test was not available at our center. The patient received curative radiotherapy daily 300 cGy for ten days. Localize dermatitis and minimal lymphocele developed on the treatment field as a complication. These lesions recovered in a few days with local symptomatic treatment. There was no residual KS after the three months completed the therapy. The patients’ follow-up continues as free of recurrence. Although epidemic and HIV-associated KS frequently involved urogenital tract, classic KS is rarely seen. The KS is mostly seen in the penis while scrotum localization is very rare. In the literature, a total number of 9 patients which are composed by HIV positive and negative patients is reported. To the best our knowledge, our case is 4th scrotal KS patient described in an HIV-negative patient.