One-pot synthesis of sulfonyl 3,6-diarylpyridazines <i>via</i> tandem condensation of α-sulfonyl ketones with methyl ketones
The tandem condensation of α-sulfonyl ketones and methyl ketones produces diverse sulfonyl pyridazines in yields of 70%-84% by one-pot Riley oxidation, Knoevenagel condensation, and sequential dehydrative imine formation.
Authors
- Chung‐Jen Ou (ORCID: https://orcid.org/0000-0002-8688-6185)
- Meng‐Yang Chang (ORCID: https://orcid.org/0000-0002-1983-8570)
Institutions
- Kaohsiung Medical University (TW)
- National Pingtung University of Science and Technology (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob01051a
- Primary Topic
- Phenothiazines and Benzothiazines Synthesis and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00