A Case of Atopic Dermatitis Combined with Crohn’s Disease

22岁男性患者,全身皮疹多年,反复腹痛3月余,加重3天入院。3个月前出现上腹部阵发性隐痛,进食后加重,便后缓解,且伴全身多处皮疹,在排除其他可能的原因后,完善胃肠镜并行病理检查,诊断为末端性回肠炎(克罗恩病?)、特应性皮炎,予JAK抑制剂乌帕替尼缓释片15 mg,po,qd治疗,后患者腹痛及全身皮疹好转出院。A 22-year-old male patient, generalised rash for many years, recurrent abdominal pain for over 3 months, admitted after worsening for 3 days. Three months ago, intermittent dull pain occurred under the xiphoid process, worsening after meals and alleviated after defecation, accompanied by generalised rash in multiple areas. After ruling out other possible causes, gastrointestinal endoscopy and pathological examination were performed, diagnosing terminal ileitis (Crohn’s disease?), atopic dermatitis. Treatment involved 15 mg of the JAK inhibitor upadacitinib sustained release tablets, taken orally once daily, leading to improvement in abdominal pain and generalised rash upon discharge.

Authors

Publication Details

Journal
Advances in Clinical Medicine
Published
2025-01-01
DOI
https://doi.org/10.12677/acm.2025.1572078
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
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article

A Case of Atopic Dermatitis Combined with Crohn’s Disease

温雅 杨
Advances in Clinical Medicine
Dermatology and Skin Diseases
article

A Case of Atopic Dermatitis Combined with Crohn’s Disease

温雅 杨
article en

Abstract

22岁男性患者,全身皮疹多年,反复腹痛3月余,加重3天入院。3个月前出现上腹部阵发性隐痛,进食后加重,便后缓解,且伴全身多处皮疹,在排除其他可能的原因后,完善胃肠镜并行病理检查,诊断为末端性回肠炎(克罗恩病?)、特应性皮炎,予JAK抑制剂乌帕替尼缓释片15 mg,po,qd治疗,后患者腹痛及全身皮疹好转出院。A 22-year-old male patient, generalised rash for many years, recurrent abdominal pain for over 3 months, admitted after worsening for 3 days. Three months ago, intermittent dull pain occurred under the xiphoid process, worsening after meals and alleviated after defecation, accompanied by generalised rash in multiple areas. After ruling out other possible causes, gastrointestinal endoscopy and pathological examination were performed, diagnosing terminal ileitis (Crohn’s disease?), atopic dermatitis. Treatment involved 15 mg of the JAK inhibitor upadacitinib sustained release tablets, taken orally once daily, leading to improvement in abdominal pain and generalised rash upon discharge.

Advances in Clinical MedicineVol. 15(07)
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