Research Progress on the Regulation of Monoamine Neurotransmitters by Acupuncture in the Treatment of Depression

抑郁症是一种严重影响患者生活质量和社会功能的精神障碍疾病，主要表现为精神不振、兴趣减退和精力不足。针刺作为传统中医疗法，在抑郁症治疗中展现出显著疗效，其机制涉及对单胺类神经递质包括五羟色胺(3-(2-Ammonioethyl)-5-hydroxy-1H-indolium maleate, 5-HT)、多巴胺(Dopamine, DA)、去甲肾上腺素(Norepinephrine, NE)、组胺(Histamine)等的调控。概述针刺研究进展通过调节单胺类神经递质改善抑郁症，为中西医结合治疗抑郁症提供理论依据，探索其可能的分子机制。Depression is a mental disorder that seriously affects the quality of life and social function of patients, mainly manifested as low spirits, reduced interest, and lack of energy. Acupuncture, as a traditional Chinese medical therapy, has shown significant efficacy in the treatment of depression, and its mechanism involves the regulation of monoamine neurotransmitters, including serotonin (3-(2-ammonioethyl)-5-hydroxy-1H-indolium maleate, 5-HT), dopamine (Dopamine, DA), norepinephrine (Norepinephrine, NE), and histamine (Histamine). This paper summarizes the research progress of acupuncture in improving depression by regulating monoamine neurotransmitters, providing a theoretical basis for the combination of traditional Chinese and Western medicine in the treatment of depression, and exploring its possible molecular mechanisms.