The effects on clinical characteristics, potential factors and outcomes in SAPHO patients during the COVID-19 epidemic
Disease activity was inversely correlated with JAK inhibitor use in SAPHO patients with COVID-19 during the pandemic. Thus, JAK antagonists have protective effects on SAPHO patients with infections and can significantly mitigate new clinical crown symptoms. However, there was a significant negative correlation between tonsillectomy and the prevalence of SAPHO with COVID-19, which demonstrates that tonsillectomy may be associated with an increased risk of COVID-19 adverse outcomes, especially in cases of taste disorders and pneumonia.
Authors
- Ziyue Huang (ORCID: https://orcid.org/0000-0002-1096-6365)
- Keqiang Zhu
- Pengfei Shen
- Minhui Su (ORCID: https://orcid.org/0000-0001-5803-6098)
- Shengyan Liu (ORCID: https://orcid.org/0000-0003-0582-7085)
- Haixu Jiang (ORCID: https://orcid.org/0000-0002-4510-7042)
- Li Chen (ORCID: https://orcid.org/0000-0002-9650-497X)
- Meiling Li (ORCID: https://orcid.org/0000-0002-1262-1897)
- Ding Zhou
Institutions
- Fujian Medical University (CN)
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Nanjing Traditional Chinese Medicine Hospital (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-07-16
- DOI
- https://doi.org/10.3389/fmed.2025.1580989
- Primary Topic
- Osteomyelitis and Bone Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00