Oligodendrocyte precursor cell transplantation attenuates inflammation after ischemic stroke in mice
This study demonstrates that oligodendrocyte precursor cell transplantation attenuates neuroinflammation and protectes blood-brain barrier in the acute phase of ischemic stroke. Our findings indicate that oligodendrocyte precursor cell transplantation is a promising therapeutic approach for ischemic stroke.
Authors
- Aijuan Yan (ORCID: https://orcid.org/0009-0002-7014-8337)
- Xinkai Qu (ORCID: https://orcid.org/0000-0001-5366-2655)
- Yuanyuan Ma (ORCID: https://orcid.org/0000-0002-2116-3306)
- Wenshi Wei (ORCID: https://orcid.org/0000-0002-1184-3164)
- Liping Wang (ORCID: https://orcid.org/0000-0001-6893-3809)
- Chang Liu (ORCID: https://orcid.org/0000-0002-1591-8354)
- Guo-Yuan Yang
Institutions
- Sun Yat-sen University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Huadong Hospital (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-07-16
- DOI
- https://doi.org/10.3389/fneur.2025.1583982
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China