Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report

Primary cardiac tumors in the fetal and neonatal populations are rare. In neonates, these tumors may present with a range of clinical manifestations, from asymptomatic cases to severe arrhythmias, valvular obstruction, and cardiac dysfunction. This report describes a case of fatal malignant arrhythmia caused by a cardiac tumor in an 8-day-old neonate. The electrocardiogram at birth revealed multiple abnormalities, including ST-T segment alterations, intraventricular conduction block, and bundle branch block. By the sixth postnatal day, the patient developed rapid, polymorphic malignant ventricular arrhythmias. Despite aggressive treatment, the neonate ultimately suffered sudden cardiac death. This case underscores the potentially fatal risk of arrhythmias associated with cardiac tumors.

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Journal
Frontiers in Cardiovascular Medicine
Published
2025-07-16
DOI
https://doi.org/10.3389/fcvm.2025.1552916
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.00

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article

Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report

Haiying Li, Hairui Li, Xin Deng, Jin Ding et al.
Frontiers in Cardiovascular Medicine
Cardiac tumors and thrombi
article

Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report

Haiying Li, Hairui Li, Xin Deng, Jin Ding, Hongmei Wu, Ge Wang, Yanhong Chen
article en

Abstract

Primary cardiac tumors in the fetal and neonatal populations are rare. In neonates, these tumors may present with a range of clinical manifestations, from asymptomatic cases to severe arrhythmias, valvular obstruction, and cardiac dysfunction. This report describes a case of fatal malignant arrhythmia caused by a cardiac tumor in an 8-day-old neonate. The electrocardiogram at birth revealed multiple abnormalities, including ST-T segment alterations, intraventricular conduction block, and bundle branch block. By the sixth postnatal day, the patient developed rapid, polymorphic malignant ventricular arrhythmias. Despite aggressive treatment, the neonate ultimately suffered sudden cardiac death. This case underscores the potentially fatal risk of arrhythmias associated with cardiac tumors.

Frontiers in Cardiovascular MedicineVol. 12
Shenzhen University (CN), University of Hong Kong - Shenzhen Hospital (CN), University of Hong Kong (HK)
Science, Technology and Innovation Commission of Shenzhen Municipality
Good health and well-being
Openalex Percentile: Top 71%
Cardiac tumors and thrombi
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Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report — Haiying Li, Hairui Li, et al. · Frontiers in Cardiovascular Medicine (2025) | TGRS Research Map | TGRS