Paroxysmal abdominalgia as a non-motor wearing off phenomenon in Parkinson’s disease. A case series and literature review

PxA is a severe, non-motor complication of PD that likely represents a form of nociplastic pain linked to dopaminergic fluctuations. Increased awareness is needed to reduce misdiagnosis and inappropriate interventions. Further research is required to elucidate underlying mechanisms and guide targeted therapy.

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Publication Details

Journal
Clinical Parkinsonism & Related Disorders
Published
2025-01-01
DOI
https://doi.org/10.1016/j.prdoa.2025.100368
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Paroxysmal abdominalgia as a non-motor wearing off phenomenon in Parkinson’s disease. A case series and literature review

Stewart A. Factor, Abdalmalik Bin Khunayfir
Clinical Parkinsonism & Related Disorders
Parkinson's Disease Mechanisms and Treatments
article

Paroxysmal abdominalgia as a non-motor wearing off phenomenon in Parkinson’s disease. A case series and literature review

Stewart A. Factor, Abdalmalik Bin Khunayfir
article en

Abstract

PxA is a severe, non-motor complication of PD that likely represents a form of nociplastic pain linked to dopaminergic fluctuations. Increased awareness is needed to reduce misdiagnosis and inappropriate interventions. Further research is required to elucidate underlying mechanisms and guide targeted therapy.

Clinical Parkinsonism & Related DisordersVol. 13
Emory University (US)
Gender equality
Openalex Percentile: Top 73%
Parkinson's Disease Mechanisms and Treatments
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